Description

9-(2-Hydroxyethyl)Guanine is a modified nucleobase derivative of guanine, featuring a hydroxymethyl side chain. This structural modification makes it a valuable intermediate in the synthesis of nucleoside analogs and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA metabolism and repair.
• Probe Development: Serves as a precursor for fluorescently labeled or modified nucleotides used in diagnostic assays.
• Organic Synthesis: Valuable chiral synthon for constructing complex molecules in medicinal chemistry.

Basic Information

Product Name	9-(2-Hydroxyethyl)Guanine
CAS No.	23169-33-7
Molecular Formula	C7H9N5O2
Molecular Weight	195.18 g/mol
Synonyms	2-Amino-9-(2-hydroxyethyl)-1,9-dihydro-6H-purin-6-one; 9-(2-Hydroxyethyl)guanine; N9-(2-Hydroxyethyl)guanine; Guanine, 9-(2-hydroxyethyl)-; 1,9-Dihydro-9-(2-hydroxyethyl)-6H-purin-6-one, 2-amino-; HE-Guanine
EINECS	Contact for details

Quality Control

Our 9-(2-Hydroxyethyl)Guanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.