Description

4-Methoxy-2-Nitrophenyl Isothiocyanate is a specialized aromatic isothiocyanate derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its unique reactivity profile, where the isothiocyanate group acts as a versatile electrophile for forming thiourea linkages, essential in constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel heterocyclic compounds, dyes, and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or containing thiourea pharmacophores.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators by incorporating the nitrophenyl moiety into active ingredients.
• Dye and Pigment Synthesis: Serves as a starting material for creating azo dyes and other colored compounds due to the presence of the nitro and methoxy functional groups.
• Polymer Modification: Employed to introduce reactive sites onto polymer backbones for creating specialty materials with tailored surface properties.
• Bioconjugation Chemistry: Useful for labeling biomolecules (proteins, peptides) via reaction with amine groups, facilitating studies in chemical biology and diagnostics.
• Ligand Synthesis for Catalysis: Building block for preparing sophisticated ligands used in transition metal catalysis for asymmetric synthesis.

Basic Information

Product Name	4-Methoxy-2-Nitrophenyl Isothiocyanate
CAS No.	23165-60-8
Molecular Formula	C8H6N2O3S
Molecular Weight	210.21 g/mol
Synonyms	2-Nitro-4-methoxyphenyl isothiocyanate; 4-Methoxy-2-nitrobenzenisothiocyanate; 1-Isothiocyanato-4-methoxy-2-nitrobenzene; 2-Nitro-4-methoxyphenyl mustard oil; 4-Methoxy-2-nitrophenyl mustard oil; (4-Methoxy-2-nitrophenyl)isothiocyanate; NSC 403107
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-Nitrophenyl Isothiocyanate undergoes rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.