Description

Physalin B is a naturally occurring, bioactive withanolide compound, a class of steroidal lactones known for their significant biological activity. This high-purity reference standard is critical for pharmaceutical research and development, enabling precise biological evaluation and analytical method validation. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and nutraceutical sectors for drug discovery and natural product analysis.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification, assay, and purity testing of Physalin B in raw materials and finished products.
• Drug Discovery & Bioactivity Screening: Serves as a key lead compound in research targeting anti-inflammatory, anti-cancer, and immunomodulatory agents.
• Natural Product Research: Employed in the isolation, characterization, and quantification of withanolides from plant extracts like Physalis species.
• Analytical Method Development: Essential for developing and validating HPLC, LC-MS, and other chromatographic methods for quality control.
• Academic & Institutional Research: Used in universities and research institutes for pharmacological studies and mechanistic investigations.
• Biomarker Studies: Potential application as a biomarker in pharmacokinetic and metabolic studies related to withanolide therapeutics.

Basic Information

Product Name	Physalin B
CAS No.	23133-56-4
Molecular Formula	C28H30O9
Molecular Weight	510.53 g/mol
Synonyms	Physalin B; (1R,2S,10S,13S,14S,17R,18S)-14,18-Epoxy-2,13-dihydroxy-1,10-dimethyl-7,20-dioxo-11,24-dioxapentacyclo[15.3.1.03,8.09,13.017,22]tetracosa-3,5,7,22-tetraene-21-carboxylic acid 6-lactone; Withanolide B (from Physalis); 14,18-Epoxy-2,13-dihydroxy-1,10-dimethyl-7,20-dioxo-11,24-dioxapentacyclo[15.3.1.03,8.09,13.017,22]tetracosa-3,5,7,22-tetraene-21-carboxylic acid δ-lactone
EINECS	Contact for details

Quality Control

Our Physalin B is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, spectroscopic identification (IR, NMR, MS), and residual solvent analysis. A detailed Certificate of Analysis (COA) providing full analytical data is supplied with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.