Description

Guanabenz Hydrochloride is a potent and selective α-2 adrenergic receptor agonist, widely recognized for its pharmacological activity. This compound is crucial for research and development in the pharmaceutical sector, particularly in the study of hypertension and neurological pathways. It serves as a key intermediate and reference standard for scientists and manufacturers in the pharmaceutical, biotechnology, and academic research industries.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) in preclinical and clinical studies.
• Neurological & Cardiovascular Research: For investigating the role of α-2 adrenergic receptors in blood pressure regulation and central nervous system functions.
• Analytical Chemistry: Used as a high-purity standard in HPLC, LC-MS, and other analytical methods for method development and validation.
• Biochemical Assays: Employed in receptor binding studies and enzyme inhibition assays to understand pharmacological mechanisms.
• Academic & Institutional Research: A vital tool for universities and research institutes studying adrenergic pharmacology.
• Contract Manufacturing: Sourced as a critical intermediate for the synthesis of more complex pharmaceutical compounds.

Basic Information

Product Name	Guanabenz Hydrochloride
CAS No.	23113-43-1
Molecular Formula	C8H8Cl2N4 • HCl
Molecular Weight	271.54 g/mol
Synonyms	Guanabenz HCl; (2,6-Dichlorobenzylidene)amino guanidine hydrochloride; 2-[(2,6-Dichlorobenzylidene)amino]guanidine hydrochloride; Wy-8678; Wyeth-8678; NSC-68967; BR-750; CI-581
EINECS	Contact for details

Quality Control

Our Guanabenz Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide material that meets rigorous in-house specifications, with comprehensive testing including identification, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.