Description

5-Methyl-5,6-Dihydrouridine is a modified nucleoside derivative of uridine, characterized by the saturation of the 5,6-double bond and a methyl group at the 5-position. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a naturally occurring modified base found in transfer RNA (tRNA), influencing RNA stability and function. It is primarily utilized by researchers and manufacturers in the fields of nucleic acid chemistry, life science research, and pharmaceutical intermediates for studying RNA modification, metabolism, and as a building block for oligonucleotide synthesis.

Application

• Biochemical Research: Used as a critical reference standard and reagent in the study of RNA modification pathways, tRNA structure, and function.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel nucleoside analogs for potential therapeutic applications.
• Life Science Reagents: Employed in enzymatic assays and as a substrate for studying RNA-modifying enzymes.
• Diagnostic Development: Can be utilized in the development of diagnostic tools and assays targeting specific RNA modifications.
• Academic Research: Essential for universities and research institutions conducting fundamental research in molecular biology and genetics.

Basic Information

Product Name	5-Methyl-5,6-Dihydrouridine
CAS No.	23067-10-9
Molecular Formula	C10H14N2O6
Molecular Weight	258.23 g/mol
Synonyms	5-Methyl-5,6-dihydro-uridine; 5-Methyldihydrouridine; 5-Methyl-DHU; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione; 5-Methyl-4,5-dihydrouridine; m5D; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-Methyl-5,6-Dihydrouridine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.