Description

δ4-Dafachronic Acid is a significant steroidal hormone and a key intermediate in the biosynthesis of dafachronic acids, which are ligands for the DAF-12 nuclear receptor. This compound matters for its crucial role in biological signaling pathways related to development and metabolism, particularly in nematodes. It is primarily needed by researchers in life sciences, pharmaceutical R&D, and biotechnology for use as a reference standard, a biochemical tool, and in the synthesis of related hormone analogs.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of DAF-12 nuclear receptor signaling and endocrine pathways.
• Pharmaceutical Development: Serves as a critical intermediate or starting material for the synthesis of novel therapeutic agents targeting hormonal regulation.
• Life Science Tools: Employed in cell-based assays and in vitro studies to investigate developmental biology and metabolic processes.
• Metabolite Analysis: Acts as an analytical standard in LC-MS or HPLC methods for the quantification of dafachronic acids in biological samples.
• Academic Research: Utilized in university and institutional labs for fundamental research in genetics, aging, and endocrinology.
• Biotechnology: Applied in the development of biosensors or screening platforms based on nuclear receptor activation.

Basic Information

Product Name	δ4-Dafachronic Acid
CAS No.	23017-97-2
Molecular Formula	C₂₇H₄₄O₃
Molecular Weight	416.64 g/mol
Synonyms	(25S)-δ⁴-Dafachronic Acid; (25S)-3-Oxo-4-cholesten-26-oic Acid; 3-Oxocholest-4-en-26-oic Acid; 4-Cholesten-26-oic acid, 3-oxo-, (25S)-; Dafachronic Acid δ4-isomer; δ4-DA; DAF-12 ligand precursor; 3-Oxo-4-cholestenoic acid
EINECS	Contact for details

Quality Control

Our δ4-Dafachronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.