Description

9-[5-o-[Hydroxy[[Hydroxy(Phosphonooxy)Phosphinyl]Oxy]Phosphinyl]-β-D-Ribofuranosyl]-9H-Purin-2-Amine is a high-purity nucleotide derivative, specifically a phosphorylated adenosine analog. This compound is of significant interest for its role as a key intermediate in biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications in enzymology, molecular biology, and as a precursor for novel therapeutic agents.

Application

• Biochemical Research: Serves as a critical substrate or intermediate in enzymatic studies, particularly those involving kinases, phosphatases, and other nucleotide-metabolizing enzymes.
• Pharmaceutical Synthesis: Acts as a key building block in the research and development of nucleotide-based drugs, including potential antivirals and anticancer agents.
• Diagnostic Reagent Development: Used in the formulation of assay kits and diagnostic reagents that require specific nucleotide analogs for detection or signal amplification.
• Enzyme Mechanism Studies: Employed to investigate the catalytic mechanisms and substrate specificity of phosphotransferase enzymes.
• Cell Signaling Research: Applied in studies of intracellular signaling pathways where adenosine phosphate derivatives play a central role.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical and research laboratories.

Basic Information

Product Name	9-[5-o-[Hydroxy[[Hydroxy(Phosphonooxy)Phosphinyl]Oxy]Phosphinyl]-β-D-Ribofuranosyl]-9H-Purin-2-Amine
CAS No.	23001-60-7
Molecular Formula	C10H17N5O13P3
Molecular Weight	508.18 g/mol
Synonyms	Adenosine 5'-(tetrahydrogen triphosphate); 2-Amino-9-(5-O-{hydroxy[hydroxy(phosphonooxy)phosphoryl]oxy}phosphinyl)-β-D-ribofuranosyl)-9H-purin-6-one; ATP (Adenosine triphosphate) analog; 9H-Purin-2-amine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-; Adenosine triphosphate derivative; 2-Aminopurine riboside triphosphate; Nucleotide triphosphate intermediate; 5'-ATP-NH2
EINECS	Contact for details

Quality Control

Our production of this nucleotide derivative adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development purposes. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity (Enzymatic Assay)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.