Description

Pregna-1,4-Diene-3,20-Dione, 11,21-Dihydroxy-17-(1-Oxobutoxy)-, (11β)- (9Ci) is a high-purity steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of potent corticosteroid APIs, enabling the production of anti-inflammatory and immunosuppressive medications. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories focused on developing next-generation therapeutic agents. Our supply ensures the stringent quality and consistency required for sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced corticosteroid active pharmaceutical ingredients (APIs).
• Anti-inflammatory Drug Research: Used in R&D for developing novel topical and systemic anti-inflammatory therapies.
• Immunosuppressant Development: Serves as a precursor in the creation of immunosuppressive drugs for autoimmune conditions and organ transplantation.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Chemistry: Utilized in scale-up and optimization studies for commercial pharmaceutical manufacturing processes.
• Academic & Institutional Research: Supports biochemical and pharmacological studies in university and institutional settings.

Basic Information

Item	Detail
Product Name	Pregna-1,4-Diene-3,20-Dione, 11,21-Dihydroxy-17-(1-Oxobutoxy)-, (11β)- (9Ci)
CAS No.	22958-20-9
Molecular Formula	C₂₅H₃₄O₇
Molecular Weight	446.53 g/mol
Synonyms	11β,21-Dihydroxy-17α-butyryloxypregna-1,4-diene-3,20-dione; 17α-Butyryloxy-11β,21-dihydroxypregna-1,4-diene-3,20-dione; Butyryloxycortisone; 17-Butyrate ester of Prednisolone; Prednisolone 17-butyrate; NSC 106977; (11β)-11,21-Dihydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our Pregna-1,4-Diene-3,20-Dione, 11,21-Dihydroxy-17-(1-Oxobutoxy)-, (11β)- (9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.