Description

1-(2-Deoxy-α-D-Erythro-Pentofuranosyl)-2(1H)-Pyridinone is a specialized nucleoside analog with significant importance in advanced pharmaceutical research and development. Its core value lies in its role as a key synthetic intermediate or building block for novel therapeutic agents, particularly in the field of antiviral and anticancer drug discovery. This high-purity compound is essential for research institutions, pharmaceutical companies, and CROs (Contract Research Organizations) engaged in the synthesis of modified nucleotides and the development of next-generation nucleic acid-based therapies.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside analog prodrugs and active pharmaceutical ingredients (APIs).
• Antiviral Research: Used in the development of potential therapeutic agents targeting viral polymerases and replication mechanisms.
• Anticancer Drug Discovery: Serves as a precursor in the creation of compounds designed to interfere with DNA synthesis in rapidly dividing cells.
• Biochemical Research: Employed in studies of enzyme kinetics, substrate specificity, and nucleic acid biochemistry.
• Proteomics & Genomics: Utilized as a modified base in the synthesis of probes and tools for genetic analysis and diagnostic applications.
• Process Development & Scale-up: Sourced by chemical development teams for route scouting, optimization, and pilot-scale synthesis under cGMP conditions.

Basic Information

Product Name	1-(2-Deoxy-α-D-Erythro-Pentofuranosyl)-2(1H)-Pyridinone
CAS No.	22882-18-4
Molecular Formula	C10H13N3O4
Molecular Weight	239.23 g/mol
Synonyms	2(1H)-Pyridinone, 1-(2-deoxy-α-D-erythro-pentofuranosyl)-; 1-(2-Deoxy-α-D-erythro-pentofuranosyl)-2(1H)-pyridinone; 2'-Deoxy-α-pseudouridine; α-dP; α-Pseudodeoxyuridine; 1-(2-Deoxy-α-D-ribofuranosyl)-2-pyridone; 2(1H)-Pyridinone, 1-(2-deoxy-α-D-ribofuranosyl)-; 1-(2-Deoxy-α-D-ribofuranosyl)-2(1H)-pyridinone
EINECS	Contact for details

Quality Control

Our 1-(2-Deoxy-α-D-Erythro-Pentofuranosyl)-2(1H)-Pyridinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our quality commitment aligns with the standards expected for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.