Description

Miconazole Nitrate CAS NO 22832-37-7 is a synthetic imidazole antifungal agent, widely recognized for its potent activity against a broad spectrum of pathogenic fungi and yeasts. Its primary value lies in its effectiveness as a key active pharmaceutical ingredient (API) for topical and systemic antifungal formulations. This compound is essential for manufacturers in the pharmaceutical, personal care, and veterinary medicine industries seeking to develop reliable antifungal treatments.

Application

• Pharmaceutical API: Primary active ingredient in topical creams, ointments, powders, and sprays for treating athlete's foot, ringworm, jock itch, and cutaneous candidiasis.
• Veterinary Medicine: Used in antifungal preparations for treating dermatological infections in companion animals and livestock.
• Personal Care Products: Incorporated into medicated soaps, shampoos, and powders for dandruff control and skin infection prevention.
• Fungal Research: Serves as a reference standard and active compound in microbiological and pharmacological research laboratories.
• Industrial Preservative: Potential application in protecting susceptible materials from fungal degradation under specific, controlled conditions.

Basic Information

Product Name	Miconazole Nitrate
CAS No.	22832-37-7
Molecular Formula	C18H14Cl4N2O·HNO3
Molecular Weight	479.15 g/mol
Synonyms	Miconazole Nitrate; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate; Micatin; Monistat; Daktarin; Andergin; Albistat; Gyno-Daktarin; (RS)-1-(2-(2,4-Dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate
EINECS	245-263-0

Quality Control

Our Miconazole Nitrate is manufactured under strict quality management systems. It is tested to meet relevant pharmacopeial standards such as USP, EP, and BP for key parameters including identification, assay, related substances, and residual solvents. A comprehensive Certificate of Analysis (COA) is provided with each batch, ensuring traceability and compliance with your specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Sulfated Ash	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C
Microbial Enumeration	Complies with EP/JP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.