Description

(22R)-3α,14,20,22,25-Pentahydroxy-5β-Cholest-7-En-6-One CAS NO 22785-88-2 is a high-purity, polyhydroxylated steroidal ketone of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral intermediate or reference standard for the development of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in steroid chemistry, drug discovery, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, metabolic pathway analysis, and receptor binding assays.
• Natural Product Synthesis: Serves as a sophisticated starting material or intermediate in the total synthesis of complex natural products with polyhydroxylated steroidal frameworks.
• Process Development & Scale-Up: Employed in process chemistry for route scouting, optimization, and the development of scalable synthetic methodologies for steroidal compounds.
• Analytical Standard: Utilized as a high-purity certified reference material (CRM) for method development, validation, and quality control in analytical laboratories.

Basic Information

Product Name	(22R)-3α,14,20,22,25-Pentahydroxy-5β-Cholest-7-En-6-One
CAS No.	22785-88-2
Molecular Formula	C₂₇H₄₄O₆
Molecular Weight	464.64 g/mol
Synonyms	3α,14,20,22,25-Pentahydroxy-5β-cholest-7-en-6-one (22R)-; (22R)-Cholest-7-ene-3,6,14,20,22,25-hexol, 5β-; 5β-Cholest-7-ene-3α,6β,14α,20,22(R),25-hexol; 3α,6β,14α,20,22(R),25-Hexahydroxy-5β-cholest-7-ene; 22R-Hydroxyecdysone; 22R-Ecdysone; Polyhydroxylated Steroid Ketone; Ecdysteroid Derivative
EINECS	Contact for details

Quality Control

Our (22R)-3α,14,20,22,25-Pentahydroxy-5β-Cholest-7-En-6-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support research and development with material that meets stringent in-house specifications, suitable for use as a reference standard or advanced intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.