Description

(S)-2-Bromopropionyl Chloride CAS NO 22592-73-0 is a high-purity chiral building block and key intermediate in organic synthesis. Its value lies in its ability to introduce the (S)-2-bromopropionyl moiety, a crucial precursor for constructing stereocenters in complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of enantiomerically pure drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where specific stereochemistry is required for efficacy.
• Peptide Chemistry: Serves as an acylating agent for the introduction of bromoalkyl groups in peptide modification and solid-phase peptide synthesis (SPPS).
• Ligand and Catalyst Preparation: A precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Science: Employed in the synthesis of functionalized monomers for creating specialty polymers with tailored properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing molecular libraries.

Basic Information

Product Name	(S)-2-Bromopropionyl Chloride
CAS No.	22592-73-0
Molecular Formula	C3H4BrClO
Molecular Weight	171.42 g/mol
Synonyms	(S)-2-Bromopropanoyl Chloride; (S)-α-Bromopropionyl Chloride; (S)-(-)-2-Bromopropionyl Chloride; L-2-Bromopropionyl Chloride; (2S)-2-Bromopropanoyl Chloride; Propionyl chloride, 2-bromo-, (S)-; Bromopropionyl chloride, (S)-; (S)-2-Bromo-1-chloropropan-1-one
EINECS	Contact for details

Quality Control

Our (S)-2-Bromopropionyl Chloride is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity, meeting the stringent requirements of advanced synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles. We adhere to cGMP principles where applicable, ensuring reliable and consistent supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.