Description

1,2-Cyclopropanedicarboxylic Anhydride, 3-(Chloroformyl)-, Stereoisomer (8Ci) is a highly reactive, multifunctional chemical building block characterized by its strained cyclopropane ring and anhydride functionality. This compound matters for its role as a key chiral intermediate in the synthesis of complex, biologically active molecules, enabling the introduction of stereochemical complexity. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• As a chiral synthon in the asymmetric synthesis of pharmaceutical intermediates.
• Key building block for the development of protease inhibitors and other enzyme-targeted therapeutics.
• Intermediate in the synthesis of advanced agrochemicals, including herbicides and fungicides with specific stereochemistry.
• Precursor for functionalized polymers and specialty materials requiring anhydride reactivity.
• Used in academic and industrial research to explore new cyclopropane-based chemical spaces.
• Starting material for the preparation of custom ligands and catalysts for asymmetric transformations.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylic Anhydride, 3-(Chloroformyl)-, Stereoisomer (8Ci)
CAS No.	22538-64-3
Molecular Formula	C6H3ClO4
Molecular Weight	174.54 g/mol
Synonyms	3-(Chloroformyl)-1,2-cyclopropanedicarboxylic Anhydride; 3-(Chlorocarbonyl)-1,2-cyclopropanedicarboxylic Acid Anhydride; 1,2-Cyclopropanedicarboxylic Anhydride, 3-(chlorocarbonyl)-; Cyclopropane-1,2-dicarboxylic Anhydride, 3-(chloroformyl)-; (1R,2S)-rel-3-(Chloroformyl)cyclopropane-1,2-dicarboxylic Anhydride; 22538-64-3; Stereoisomer of Chloroformylcyclopropanedicarboxylic Anhydride
EINECS	Contact for details

Quality Control

Our 1,2-Cyclopropanedicarboxylic Anhydride, 3-(Chloroformyl)-, Stereoisomer (8Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure consistent quality and stereochemical integrity for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.