Description

2-Chloro-5,6-Dimethyl-1-.Beta.-D-Ribofuranosylbenzimidazole is a specialized nucleoside analog with a benzimidazole base, offering a unique scaffold for advanced chemical synthesis and research. This compound matters for its role as a critical building block in the development of novel pharmaceutical intermediates and biochemical probes. It is primarily needed by research institutions and pharmaceutical companies engaged in antiviral, anticancer, and nucleoside chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and polymerase function.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Life Science Reagent: Utilized in the development of molecular probes and diagnostic tools.

Basic Information

Product Name	2-Chloro-5,6-Dimethyl-1-.Beta.-D-Ribofuranosylbenzimidazole
CAS No.	22423-14-9
Molecular Formula	C14H17ClN2O4
Molecular Weight	312.75 g/mol
Synonyms	2-Chloro-5,6-dimethyl-1-β-D-ribofuranosyl-1H-benzimidazole; 2-Chloro-5,6-dimethyl-1-(β-D-ribofuranosyl)benzimidazole; 1-(2-Chloro-5,6-dimethyl-1H-benzimidazol-1-yl)-1-deoxy-β-D-ribofuranose; 2-Chloro-5,6-dimethyl-1-(β-D-ribofuranosyl)-1H-benzimidazole; 2-Chloro-5,6-dimethyl-1-β-D-ribofuranosyl-1H-benzimidazole; 2-Chloro-5,6-dimethyl-1-(β-D-ribofuranosyl)-1H-benzimidazole; 2-Chloro-5,6-dimethyl-1-(β-D-ribofuranosyl)benzimidazole
EINECS	Contact for details

Quality Control

Our 2-Chloro-5,6-Dimethyl-1-.Beta.-D-Ribofuranosylbenzimidazole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.