Description

(3S,5S,10S,13R,17R)-4,4,10,13,14-Pentamethyl-17-Propan-2-Yl-2,3,5,6,7, 11,12,15,16,17-Decahydro-1H-Cyclopenta[A]Phenanthren-3-Ol is a high-purity sterol derivative with a defined stereochemistry, serving as a critical advanced intermediate in complex organic synthesis. Its precise molecular architecture makes it an invaluable building block for research and development in life sciences, enabling the creation of novel compounds with targeted biological activity. This compound is essential for pharmaceutical chemists and R&D laboratories focused on steroid chemistry, drug discovery, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in studies involving sterol metabolism, receptor binding, and enzymatic pathways.
• Organic Synthesis: Serves as a sophisticated starting material or intermediate for constructing complex polycyclic structures in academic and industrial research.
• Drug Discovery: Employed in medicinal chemistry programs to explore structure-activity relationships (SAR) for new drug candidates targeting hormonal or metabolic pathways.
• Fine Chemical Production: Utilized in the multi-step synthesis of high-value specialty chemicals and performance materials.

Basic Information

Product Name	(3S,5S,10S,13R,17R)-4,4,10,13,14-Pentamethyl-17-Propan-2-Yl-2,3,5,6,7, 11,12,15,16,17-Decahydro-1H-Cyclopenta[A]Phenanthren-3-Ol
CAS No.	22415-20-9
Molecular Formula	C26H44O
Molecular Weight	372.64 g/mol
Synonyms	3β-Hydroxy-4,4,10,13,14-pentamethyl-17-(1-methylethyl)-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene; (3β)-4,4,10,13,14-Pentamethyl-17-(1-methylethyl)-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol; 3β-Hydroxy-4,4,10,13,14-pentamethyl-17-isopropyl-1,2,3,5,6,7,10,11,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene; Sterol derivative 22415-20-9; Pentamethyl-isopropyl-sterol; 3-Hydroxy-4,4,10,13,14-pentamethyl-17-isopropyl-perhydrocyclopenta[a]phenanthrene
EINECS	Contact for details

Quality Control

Our (3S,5S,10S,13R,17R)-4,4,10,13,14-Pentamethyl-17-Propan-2-Yl-2,3,5,6,7, 11,12,15,16,17-Decahydro-1H-Cyclopenta[A]Phenanthren-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research-grade intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, chiral purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.