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3-Aminopropyl-[[5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methyl]-Methyl-Sulfonium CAS NO 22365-13-5


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CAS No.:22365-13-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Aminopropyl-[[5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methyl]-Methyl-Sulfonium is a specialized biochemical compound, a sulfonium derivative of adenosine, which serves as a crucial intermediate in advanced organic synthesis and biochemical research. Its primary value lies in its role as a precursor for synthesizing modified nucleosides and nucleotides, which are essential for studying enzyme mechanisms, metabolic pathways, and developing novel therapeutic agents. This high-purity intermediate is particularly vital for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on nucleic acid chemistry, epigenetics, and medicinal chemistry.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of novel adenosine analogs and nucleoside-based prodrugs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving methyltransferases and other sulfur-utilizing enzymes.
  • Nucleic Acid Chemistry: Serves as a precursor for labeled nucleotides used in tracing metabolic pathways or in diagnostic assay development.
  • Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new therapeutic candidates targeting various diseases.
  • Life Science Reagents: A component in the manufacture of high-grade research reagents and kits for molecular biology.

Basic Information

Item Details
Product Name 3-Aminopropyl-[[5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methyl]-Methyl-Sulfonium
CAS No. 22365-13-5
Molecular Formula C14H22N6O3S
Molecular Weight 354.43 g/mol
Synonyms S-Adenosylmethionine Analogue; 3-Aminopropyl-methyl-sulfonium adenosine; Modified S-Adenosylmethionine; Adenosylmethionine sulfonium derivative; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-[[(3-aminopropyl)methylsulfonio]methyl]oxolan-2-yl]purin-6-amine; 6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[[(3-aminopropyl)methylsulfonio]methyl]oxolan-2-yl]-1H-purin-1-ium
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Quality Control

Every batch of our 3-Aminopropyl-[[5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methyl]-Methyl-Sulfonium is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 95.0%
Assay ≥ 97.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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