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3-Aminopropyl-[[5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methyl]-Methyl-Sulfonium CAS NO 22365-13-5
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CAS No.:22365-13-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Aminopropyl-[[5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methyl]-Methyl-Sulfonium is a specialized biochemical compound, a sulfonium derivative of adenosine, which serves as a crucial intermediate in advanced organic synthesis and biochemical research. Its primary value lies in its role as a precursor for synthesizing modified nucleosides and nucleotides, which are essential for studying enzyme mechanisms, metabolic pathways, and developing novel therapeutic agents. This high-purity intermediate is particularly vital for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on nucleic acid chemistry, epigenetics, and medicinal chemistry.
Application
- Pharmaceutical Intermediate: Key building block for the synthesis of novel adenosine analogs and nucleoside-based prodrugs.
- Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving methyltransferases and other sulfur-utilizing enzymes.
- Nucleic Acid Chemistry: Serves as a precursor for labeled nucleotides used in tracing metabolic pathways or in diagnostic assay development.
- Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new therapeutic candidates targeting various diseases.
- Life Science Reagents: A component in the manufacture of high-grade research reagents and kits for molecular biology.
Basic Information
| Item | Details |
|---|---|
| Product Name | 3-Aminopropyl-[[5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methyl]-Methyl-Sulfonium |
| CAS No. | 22365-13-5 |
| Molecular Formula | C14H22N6O3S |
| Molecular Weight | 354.43 g/mol |
| Synonyms | S-Adenosylmethionine Analogue; 3-Aminopropyl-methyl-sulfonium adenosine; Modified S-Adenosylmethionine; Adenosylmethionine sulfonium derivative; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-[[(3-aminopropyl)methylsulfonio]methyl]oxolan-2-yl]purin-6-amine; 6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[[(3-aminopropyl)methylsulfonio]methyl]oxolan-2-yl]-1H-purin-1-ium |
| EINECS | Contact for details |
Quality Control
Every batch of our 3-Aminopropyl-[[5-(6-Aminopurin-9-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methyl]-Methyl-Sulfonium is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 95.0% |
| Assay | ≥ 97.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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