Description

3α-Acetoxy-5α-Androstane is a high-purity steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of hormonal therapies and other specialized medicinal compounds. The consistent quality and reliable supply of this intermediate are paramount for ensuring the integrity of downstream synthesis processes.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of steroidal drugs and hormonal agents.
• Research & Development: Used in medicinal chemistry for exploring new therapeutic compounds and metabolic pathways.
• Reference Standard: Serves as an analytical standard for quality control and method validation in steroid analysis.
• Biochemical Studies: Employed in laboratory studies to investigate steroid hormone action and receptor binding.
• Process Chemistry: Utilized for process optimization and scale-up studies in API manufacturing.

Basic Information

Product Name	3α-Acetoxy-5α-Androstane
CAS No.	22265-06-1
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	5α-Androstan-3α-yl acetate; Androstane-3α-ol acetate; 3α-Hydroxy-5α-androstan-17-one 3-acetate; 3α-Acetoxyandrostane; 5α-Androstan-3α-ol, acetate; 3α-Acetoxy-5α-androstan-17-one; 17-Oxo-5α-androstan-3α-yl acetate
EINECS	Contact for details

Quality Control

Our 3α-Acetoxy-5α-Androstane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for pharmaceutical-grade intermediates. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.