Description

7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxamidoxime, 4-Amino-7-.Beta.-D-Ribo Furanosyl- is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the creation of novel antiviral and anticancer agents, particularly those targeting nucleic acid synthesis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of nucleoside-based therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analog drugs, including potential antiviral and anticancer candidates.
• Antiviral Drug Research: Used in the development of therapeutics targeting viruses such as hepatitis and herpes, which rely on nucleoside metabolism.
• Oncology Research: Serves as a precursor in the design of chemotherapeutic agents that act as antimetabolites to disrupt DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleoside-processing pathways.
• Fine Chemical Synthesis: A specialized intermediate for custom synthesis and contract manufacturing of complex, high-value organic molecules.
• Academic Research: Used in university and institutional labs for studying structure-activity relationships (SAR) of modified nucleosides.

Basic Information

Product Name	7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxamidoxime, 4-Amino-7-.Beta.-D-Ribo Furanosyl-
CAS No.	22242-89-3
Molecular Formula	C12H16N6O5
Molecular Weight	324.29 g/mol
Synonyms	4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime; Tubercidin 5'-Carboxamidoxime; 7-Deazaadenosine-5-carboxamidoxime; 4-Amino-5-carbamoyl-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine; TBCA; 4-Amino-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamidoxime
EINECS	Contact for details

Quality Control

Our 7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxamidoxime, 4-Amino-7-.Beta.-D-Ribo Furanosyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.