Description

Guanadrel Hemisulfate is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API). This compound is critical for the research and development of antihypertensive agents, functioning as a postganglionic adrenergic blocking agent. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers focused on cardiovascular therapeutics. Consistent quality and reliable supply are paramount for its effective integration into advanced drug formulations.

Application

• Pharmaceutical API: Primary use as an active ingredient in the formulation of antihypertensive medications.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies of adrenergic neurotransmission and blood pressure regulation.
• Fine Chemical Synthesis: Serves as a key intermediate in the synthesis of more complex, specialized pharmaceutical molecules.
• Analytical Standard: Employed in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for managing hypertension in animals.

Basic Information

Product Name	Guanadrel Hemisulfate
CAS No.	22195-34-2
Molecular Formula	C10H24N4O4S
Molecular Weight	296.39 g/mol
Synonyms	Guanadrel Sulfate (1:1); Guanadrel Hydrogen Sulfate; (1,4-Dioxaspiro[4.5]dec-2-ylmethyl)guanidine Hemisulfate; 2-[(1,4-Dioxaspiro[4.5]dec-2-yl)methyl]guanidine Hemisulfate; Guanadrel Monosulfate; Guanadrel Sulphate; CL 1388R; Wy-15211
EINECS	Contact for details

Quality Control

Our Guanadrel Hemisulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.