Description

(17R)-3β,8β,11α,12β,14β-Pentahydroxypregna-5-Ene-20-One is a high-purity, multi-hydroxylated pregnane derivative, a key intermediate in the synthesis of complex steroid-based pharmaceuticals. Its precise stereochemistry and functional group array make it a valuable building block for research and development in advanced therapeutic areas. This compound is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions focused on steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel steroidal drugs, including potential anti-inflammatory, neuroactive, or hormonal agents.
• Biochemical Research: Used as a reference standard or precursor in studies investigating steroid biosynthesis pathways, enzyme mechanisms, and receptor interactions.
• Process Chemistry Development: Serves as a starting material or intermediate for optimizing synthetic routes to more complex, biologically active steroid molecules in a GMP or non-GMP environment.
• Academic & Contract Research: Employed in university and CRO settings for methodological development in organic synthesis, asymmetric catalysis, and natural product chemistry.

Basic Information

Item	Details
Product Name	(17R)-3β,8β,11α,12β,14β-Pentahydroxypregna-5-Ene-20-One
CAS No.	22149-67-3
Molecular Formula	C21H32O6
Molecular Weight	380.48 g/mol
Synonyms	3β,8β,11α,12β,14β-Pentahydroxypregn-5-en-20-one; 17R-Pentahydroxypregnenolone; 3β,8β,11α,12β,14β-Pentahydroxy-5-pregnen-20-one; (17R)-Pentahydroxypregna-5-ene-20-one; 5-Pregnene-3β,8β,11α,12β,14β-pentol-20-one
EINECS	Contact for details

Quality Control

Our (17R)-3β,8β,11α,12β,14β-Pentahydroxypregna-5-Ene-20-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container is opened.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.