Description

(17S,20R)-Pregna-5-Ene-3β,11α,12β,14β,20-Pentol is a high-purity, multi-hydroxylated pregnane derivative, a key intermediate in the synthesis of complex steroid-based pharmaceuticals. Its precise stereochemistry and functional group array make it a valuable building block for research and development in medicinal chemistry. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on producing novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of advanced steroid drugs and hormone analogs.
• Medicinal Chemistry Research: Used as a scaffold or precursor in the discovery and development of new bioactive molecules targeting specific receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and metabolic processes.
• Process Development: Used in optimizing synthetic routes for the scalable production of complex steroid compounds.

Basic Information

Product Name	(17S,20R)-Pregna-5-Ene-3β,11α,12β,14β,20-Pentol
CAS No.	22149-59-3
Molecular Formula	C21H32O5
Molecular Weight	364.48 g/mol
Synonyms	3β,11α,12β,14β,20-Pentahydroxypregn-5-ene; (17S,20R)-3β,11α,12β,14β,20-Pentahydroxypregn-5-ene; 3β,11α,12β,14β,20-Pentahydroxy-5-pregnene; Pregna-5-ene-3β,11α,12β,14β,20-pentol; 5-Pregnene-3β,11α,12β,14β,20-pentol
EINECS	Contact for details

Quality Control

Our (17S,20R)-Pregna-5-Ene-3β,11α,12β,14β,20-Pentol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.