Description

Bicyclo[2.2.2]Oct-2-Ene-1-Carbonyl Chloride, 4-Methyl- (8Ci,9Ci) is a highly reactive and versatile bicyclic acid chloride derivative. This compound matters as a critical building block in advanced organic synthesis, enabling the introduction of the strained bicyclo[2.2.2]octene scaffold into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly those requiring rigid, three-dimensional core structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific steric and binding properties.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials with unique thermal or mechanical characteristics.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including cycloaddition reactions and cross-coupling protocols.
• Fine Chemical Production: Integral in the multi-step synthesis of complex fragrance and flavor ingredients.

Basic Information

Product Name	Bicyclo[2.2.2]Oct-2-Ene-1-Carbonyl Chloride, 4-Methyl- (8Ci,9Ci)
CAS No.	22148-41-0
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	4-Methylbicyclo[2.2.2]oct-2-ene-1-carbonyl chloride; 4-Methyl-2,5-norbornadiene-1-carbonyl chloride; 1-Chlorocarbonyl-4-methylbicyclo[2.2.2]oct-2-ene; 4-Methylbicyclo[2.2.2]oct-2-ene-1-carboxylic acid chloride; 4-Methyl-2,5-norbornadiene-1-carboxylic acid chloride; 4-Methyl-2,5-norbornadiene-1-carbonyl chloride; 1-Carbonyl chloride-4-methylbicyclo[2.2.2]oct-2-ene
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Oct-2-Ene-1-Carbonyl Chloride, 4-Methyl- (8Ci,9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.