Description

7β,8-Epoxy-3β,11α,14-Trihydroxy-12-Oxo-5β-Card-20(22)-Enolide is a high-purity, specialized cardiac glycoside derivative. This compound is of significant interest in pharmaceutical research and development, particularly for its structural relationship to bioactive natural products. It serves as a critical advanced intermediate or reference standard for scientists in the life sciences sector. Target users include R&D laboratories and manufacturers focused on cardiovascular drug discovery, process chemistry, and analytical method development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic building block in the research and production of novel cardiac-active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) of cardenolide and bufadienolide compounds.
• Process Development: Utilized in scaling up synthetic routes for complex steroid-derived molecules in process chemistry.

Basic Information

Product Name	7β,8-Epoxy-3β,11α,14-Trihydroxy-12-Oxo-5β-Card-20(22)-Enolide
CAS No.	22146-03-8
Molecular Formula	C₂₃H₃₀O₈
Molecular Weight	434.48 g/mol
Synonyms	12-Oxocardenolide; 3β,11α,14-Trihydroxy-12-oxo-7β,8-epoxy-5β-card-20(22)-enolide; 7β,8-Epoxy-3β,11α,14-trihydroxy-12-oxo-5β,20(22)-cardenolide; 12-Oxo-3β,11α,14-trihydroxy-7β,8-epoxy-5β-card-20(22)-enolide; 7β,8α-Epoxy-3β,11α,14-trihydroxy-12-oxo-5β-card-20(22)-enolide; 12-Oxocarden; 7β,8-Epoxycardenolide derivative
EINECS	Contact for details

Quality Control

Our 7β,8-Epoxy-3β,11α,14-Trihydroxy-12-Oxo-5β-Card-20(22)-Enolide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under appropriate conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.