Description

2,4,6-Tribromophenyl Isothiocyanate is a specialized organobromine compound that serves as a versatile building block in advanced organic synthesis. Its high reactivity, particularly through the isothiocyanate functional group, makes it a critical intermediate for creating complex molecules with tailored properties. This product is essential for researchers and manufacturers in the agrochemical and pharmaceutical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those requiring brominated aromatic scaffolds for bioactivity.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, where the tribromophenyl moiety can enhance stability and efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalytic processes.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, or organic electronic materials that benefit from bromine's properties.
• Chemical Biology Probes: Useful for synthesizing affinity probes or tags for studying biological systems due to the reactive isothiocyanate group.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct complex biaryl structures.

Basic Information

Product Name	2,4,6-Tribromophenyl Isothiocyanate
CAS No.	22134-11-8
Molecular Formula	C7H2Br3NS
Molecular Weight	375.78 g/mol
Synonyms	2,4,6-Tribromophenyl isothiocyanate; Isothiocyanic acid, 2,4,6-tribromophenyl ester; 1-Isothiocyanato-2,4,6-tribromobenzene; NSC 404087; 2,4,6-Tribromo-1-isothiocyanatobenzene; 2,4,6-Tribromobenzene isothiocyanate; 2,4,6-Tribromophenyl mustard oil
EINECS	Contact for details

Quality Control

Our 2,4,6-Tribromophenyl Isothiocyanate is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. We are committed to meeting the stringent requirements of research and development as well as scale-up manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.