Description

2,4,6-Trichlorophenyl Isothiocyanate is a versatile and highly reactive organosulfur compound characterized by its isothiocyanate functional group attached to a symmetrically substituted trichlorophenyl ring. This structure makes it a valuable key synthetic intermediate for constructing more complex molecules, particularly in the development of agrochemicals and pharmaceuticals. It is primarily sought after by research institutions, fine chemical manufacturers, and agrochemical formulators for its role in synthesizing thiourea derivatives, heterocyclic compounds, and potential bioactive agents.

Application

• Agrochemical Intermediate: A crucial building block for the synthesis of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create thiourea and related compounds.
• Pharmaceutical Research: Serves as a key precursor in medicinal chemistry for developing potential drug candidates, especially those targeting enzyme inhibition.
• Dye and Pigment Synthesis: Used in the production of specialized dyes and pigments where the isothiocyanate group facilitates covalent bonding to substrates or other chromophores.
• Polymer Modification: Acts as a reactive agent for introducing functional groups into polymer chains to alter material properties like adhesion or biocompatibility.
• Cross-linking Agent: Employed in biochemical and material science applications to cross-link proteins or polymers due to its high reactivity with amine groups.
• Chemical Synthesis Reagent: A versatile reagent in organic synthesis for constructing heterocycles such as thiazoles and benzothiazoles.

Basic Information

Product Name	2,4,6-Trichlorophenyl Isothiocyanate
CAS No.	22134-07-2
Molecular Formula	C7H2Cl3NS
Molecular Weight	238.52 g/mol
Synonyms	2,4,6-Trichlorophenyl isothiocyanate; Isothiocyanic acid, 2,4,6-trichlorophenyl ester; 2,4,6-Trichlorophenyl mustard oil; 2,4,6-Trichlorobenzene isothiocyanate; NSC 403107; 2,4,6-Trichlorophenylthiocarbonimide; (2,4,6-Trichlorophenyl)isothiocyanate
EINECS	244-780-6

Quality Control

Our 2,4,6-Trichlorophenyl Isothiocyanate is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to meet the stringent requirements of research and industrial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from strong bases and open flames. Keep under an inert atmosphere if long-term storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.