Description

2(1H)-Pyrimidinone, 1-(2-Deoxy-β-D-Erythro-Pentofuranosyl)-5-Methyl is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate in the synthesis of novel therapeutic agents, particularly in the field of antiviral and anticancer drug discovery. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of prodrugs targeting viral polymerases for diseases such as hepatitis and herpes.
• Oncology Research: Serves as a scaffold for creating chemotherapeutic agents that interfere with DNA replication in cancer cells.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleotide metabolism pathways.
• Prodrug Development: Utilized to design masked nucleotide analogs with improved bioavailability and targeted delivery.
• Fine Chemical Synthesis: A specialized building block for custom synthesis and contract manufacturing of high-value active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	2(1H)-Pyrimidinone, 1-(2-Deoxy-β-D-Erythro-Pentofuranosyl)-5-Methyl
CAS No.	22003-31-2
Molecular Formula	C10H14N2O5
Molecular Weight	242.23 g/mol
Synonyms	5-Methyl-2'-deoxyuridine; Thymidine, 2'-deoxy-; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 5-Methyldeoxyuridine; dT; 2'-Deoxythymidine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinone, 1-(2-Deoxy-β-D-Erythro-Pentofuranosyl)-5-Methyl is manufactured under strict quality management systems. We offer material suitable for research and development purposes, with purity levels typically exceeding 95% (HPLC). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Specifications can be tailored to meet the requirements of cGMP and other stringent pharmaceutical guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.