Description

(8R,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-Methylidene-1,2,6,7,8,9,11,12,14,15,16,17-Dodecahydrocyclopenta[A]Phenanthren-17-Ol is a high-purity sterol derivative, serving as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. Its defined stereochemistry and functional groups make it invaluable for the research and development of novel therapeutic agents and fine chemicals. This compound is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of steroidal drugs, hormones, and related bioactive molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Fine Chemical Synthesis: Serves as a sophisticated building block for constructing complex polycyclic frameworks in organic synthesis.
• Biochemical Research: Potential use as a probe or standard in biochemical assays studying sterol metabolism and receptor interactions.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	(8R,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-Methylidene-1,2,6,7,8,9,11,12,14,15,16,17-Dodecahydrocyclopenta[A]Phenanthren-17-Ol
CAS No.	21952-93-2
Molecular Formula	C20H30O
Molecular Weight	286.46 g/mol
Synonyms	3-Methyleneandrostan-17-ol; 17-Hydroxy-3-methylenandrostane; 3-Methylene-5α-androstan-17β-ol; 3-Methylenandrostan-17β-ol; (5α)-3-Methyleneandrostan-17β-ol; 3-Methylenandrostan-17-ol; 17β-Hydroxy-3-methylenandrostane; 3-Methylene-17β-hydroxyandrostane
EINECS	Contact for details

Quality Control

Our production of this sterol derivative adheres to stringent quality protocols suitable for pharmaceutical-grade intermediates. Every batch is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.