Description

(22R)-5β,6β-Epoxy-3-Methoxy-1-Oxo-4β,22,27-Trihydroxyergost-24-En-26-Oic Acid 26,22-Lactone is a high-purity, complex ergostane-type steroidal lactone of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of bioactive molecules with potential therapeutic applications. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in steroid chemistry, oncology research, and metabolic studies.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in studies of enzyme inhibition, receptor binding, and metabolic pathways.
• Academic Research: Employed in university and institutional labs for investigating the structure-activity relationships (SAR) of complex natural products.
• Fine Chemical Synthesis: Serves as a starting material for the preparation of specialized derivatives for high-value chemical applications.
• Quality Control & Analytical Standards: Provides a certified reference material for HPLC, LC-MS, and NMR analysis to ensure product purity and identity in manufacturing.

Basic Information

Product Name	(22R)-5β,6β-Epoxy-3-Methoxy-1-Oxo-4β,22,27-Trihydroxyergost-24-En-26-Oic Acid 26,22-Lactone
CAS No.	21902-96-5
Molecular Formula	C₂₉H₄₀O₈
Molecular Weight	516.63 g/mol
Synonyms	5β,6β-Epoxy-3-methoxy-1-oxo-4β,22,27-trihydroxyergost-24-en-26-oic acid 26,22-lactone; (22R)-Ergostane lactone derivative; 22R-Epoxyergostanolide; 21902-96-5; 4β,22,27-Trihydroxy-5β,6β-epoxy-3-methoxy-1-oxoergost-24-en-26-oic acid δ-lactone; Steroidal epoxy lactone
EINECS	Contact for details

Quality Control

Our (22R)-5β,6β-Epoxy-3-Methoxy-1-Oxo-4β,22,27-Trihydroxyergost-24-En-26-Oic Acid 26,22-Lactone is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP and ISO compliant processes for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.