Description

4-Isopropylbenzoyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 4-isopropylbenzoyl moiety, enabling the production of high-value fine chemicals and functional materials. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with tailored properties.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring the cumyl (4-isopropylbenzoyl) functional group.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators where its lipophilic isopropyl group enhances bioactivity.
• Polymer Chemistry: Acts as a monomer or modifying agent for producing specialty polymers, including polyamides and polyesters with specific thermal and mechanical properties.
• Liquid Crystal & OLED Materials: Serves as a building block for synthesizing advanced organic electronic materials and liquid crystal display (LCD) components.
• Dye & Pigment Manufacturing: Intermediate in the production of complex organic dyes and pigments, contributing to color fastness and stability.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation, esterification, and amidation reactions to create ketones, esters, and amides under mild conditions.
• Flavor & Fragrance Industry: Used in the controlled synthesis of aromatic esters that serve as key components in fragrances and flavors.

Basic Information

Item	Details
Product Name	4-Isopropylbenzoyl Chloride
CAS No.	21900-62-9
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	p-Isopropylbenzoyl Chloride; Cumoyl Chloride; 4-(1-Methylethyl)benzoyl Chloride; 1-(Chlorocarbonyl)-4-isopropylbenzene; p-Cumyl Chloroformate; Isopropylbenzoyl Chloride; (4-Isopropylphenyl)carbonyl Chloride
EINECS	244-645-9

Quality Control

Our 4-Isopropylbenzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards demanded by pharmaceutical and fine chemical customers globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat and incompatible materials. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and degradation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (HPLC)	≤ 1.0% (Total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.