Description

2-Chloro-4-Fluorobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 2-chloro-4-fluorobenzoyl moiety, a key structural motif in the development of high-value compounds. This intermediate is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing the benzoyl chloride functional group.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and insecticides, where the chloro-fluoro substitution pattern enhances biological activity.
• Liquid Crystal & OLED Material Production: Serves as a building block for advanced electronic materials and display technologies.
• Polymer & Resin Modification: Employed to introduce functional groups into polymer chains, altering physical and chemical properties for specialized applications.
• Dyestuff & Pigment Manufacturing: Intermediate in the production of complex dyes and high-performance pigments.
• Custom Synthesis & R&D: A valuable reagent for contract research organizations and academic laboratories exploring novel chemical entities.

Basic Information

Product Name	2-Chloro-4-Fluorobenzoyl Chloride
CAS No.	21900-54-9
Molecular Formula	C7H3Cl2FO
Molecular Weight	193.00 g/mol
Synonyms	2-Chloro-4-fluorobenzoic acid chloride; 4-Fluoro-2-chlorobenzoyl chloride; Benzoic acid, 2-chloro-4-fluoro-, chloride; 2-Chloro-4-fluorobenzenecarbonyl chloride; o-Chloro-p-fluorobenzoyl chloride; 2-Chloro-4-fluorobenzoylchloride; 21900-54-9; NSC 403119
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.