Description

Benzoyl Chloride, 4-Bromo-2-Methyl- CAS NO 21900-45-8 is a halogenated benzoyl chloride derivative serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic positioning of both the bromo and methyl substituents on the aromatic ring, which enables selective functionalization and the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active compounds and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzoyl moiety.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the bromo-methyl-benzoyl structure imparts specific biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays and organic light-emitting diodes.
• Polymer & Resin Modification: Employed to introduce functional groups into polymer chains, enhancing properties like adhesion, thermal stability, or reactivity.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex dyes and organic pigments, contributing to color fastness and specific hue properties.
• Cross-Coupling Reactions: The bromine atom makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.

Basic Information

Item	Detail
Product Name	Benzoyl Chloride, 4-Bromo-2-Methyl-
CAS No.	21900-45-8
Molecular Formula	C8H6BrClO
Molecular Weight	233.49 g/mol
Synonyms	4-Bromo-2-methylbenzoyl chloride; 2-Methyl-4-bromobenzoyl chloride; 4-Bromo-o-toluoyl chloride; (4-Bromo-2-methylphenyl)methanone chloride; α-Chloro-4-bromo-2-methylacetophenone; 4-Bromo-2-methylbenzoic acid chloride
EINECS	Contact for details

Quality Control

Our Benzoyl Chloride, 4-Bromo-2-Methyl- is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.