Description

4-Fluoro-2-Methylbenzoyl Chloride is a high-purity, versatile organic intermediate essential for advanced chemical synthesis. This compound is valued for its reactive acid chloride group and substituted aromatic ring, which enable precise functionalization in complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

This specialized benzoyl chloride derivative serves as a critical building block in several high-value industrial and research applications.

• Pharmaceutical Intermediates: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the 4-fluoro-2-methyl substitution pattern enhances biological activity.
• Liquid Crystal & OLED Materials: Acts as a starting material for synthesizing fluorinated aromatic components used in electronic display technologies.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce fluorinated aromatic units into polymer chains, altering material properties.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for constructing complex molecules, including ligands for catalysis.
• Dye & Pigment Intermediates: Used in the synthesis of specialized dyes and pigments where fluorine substitution improves lightfastness and color properties.

Basic Information

Product Name	4-Fluoro-2-Methylbenzoyl Chloride
CAS No.	21900-43-6
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	2-Methyl-4-fluorobenzoyl chloride; 4-Fluoro-o-toluoyl chloride; 4-Fluoro-2-methylbenzoic acid chloride; 2-Methyl-4-fluorobenzoic acid chloride; α,4-Difluoro-o-toluoyl chloride (incorrect but common misnomer); 4-Fluoro-2-methylbenzoyl chloride; 21900-43-6; 4-Fluoro-2-methyl-benzoic acid chloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methylbenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standard of 99% minimum and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Water Content (Karl Fischer)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.