Description

5-Bromo-2-Methylbenzoyl Chloride CAS NO 21900-41-4 is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 5-bromo-2-methylbenzoyl moiety into target molecules, enabling the creation of complex chemical architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients, functional polymers, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated benzoyl group.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the bromine and methyl substituents can modulate biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Polymer and Material Science: Employed in the production of specialty polymers, liquid crystals, and organic electronic materials due to its reactive acid chloride group and aromatic structure.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring novel chemical entities and reaction pathways.

Basic Information

Product Name	5-Bromo-2-Methylbenzoyl Chloride
CAS No.	21900-41-4
Molecular Formula	C8H6BrClO
Molecular Weight	233.49 g/mol
Synonyms	2-Methyl-5-bromobenzoyl chloride; 5-Bromo-o-toluoyl chloride; 5-Bromo-2-methylbenzoic acid chloride; (5-Bromo-2-methylphenyl)carbonyl chloride; 5-Bromo-2-methyl-benzoylchlorid; Benzoyl chloride, 5-bromo-2-methyl-; 21900-41-4
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methylbenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.