Description

3-Bromo-4-Chlorobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 3-bromo-4-chlorobenzoyl moiety into target molecules, enabling the creation of complex chemical architectures. This intermediate is essential for research and production in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated benzoyl groups.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and pesticides, where its halogenated structure contributes to biological activity.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or modifying agent in the production of specialty polymers and liquid crystal materials.
• Dyestuff & Pigment Production: Intermediate for synthesizing complex organic dyes and high-performance pigments.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for amide bond formation, Friedel-Crafts acylation, and other coupling reactions.
• Chemical Research: Serves as a standard or starting material in methodological development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Bromo-4-Chlorobenzoyl Chloride
CAS No.	21900-34-5
Molecular Formula	C7H3BrCl2O
Molecular Weight	253.91 g/mol
Synonyms	4-Chloro-3-bromobenzoyl chloride; 3-Bromo-4-chlorobenzoic acid chloride; 3-Bromo-4-chlorobenzenecarbonyl chloride; Benzoic acid, 3-bromo-4-chloro-, chloride; 3-Bromo-p-chlorobenzoyl chloride; (3-Bromo-4-chlorophenyl)carbonyl chloride; α-Chloro-3-bromo-4-chlorotoluene
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chlorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.