Description

3-Bromo-5-Chlorobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which allows for selective and sequential functionalization, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the bromine and chlorine substituents contribute to biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating halogenated aromatic cores in electronic chemicals for display and lighting technologies.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce aromatic and halogenated units into high-performance polymers.
• Dyestuff & Pigment Manufacturing: Intermediate for synthesizing specialized azo dyes and high-stability pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings due to the reactive bromine atom.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	3-Bromo-5-Chlorobenzoyl Chloride
CAS No.	21900-27-6
Molecular Formula	C7H3BrCl2O
Molecular Weight	253.91 g/mol
Synonyms	5-Chloro-3-bromobenzoyl chloride; 3-Bromo-5-chlorobenzoic acid chloride; m-Bromo-m'-chlorobenzoyl chloride; Benzoyl chloride, 3-bromo-5-chloro-; 3-Bromo-5-chlorobenzenecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chlorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for use in cGMP-compliant pharmaceutical synthesis and other high-value applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and bases. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture absorption. Isolate from strong oxidizing agents, strong bases, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.