Description

4-tert-Butylphenacyl Chloride is a versatile and reactive organic intermediate, primarily recognized as a key building block in fine chemical synthesis. Its value lies in its ability to introduce the 4-tert-butylphenacyl moiety, a functional group of significant interest in advanced material and pharmaceutical research. This compound is essential for research chemists and process development scientists working in the fields of specialty chemicals, agrochemicals, and pharmaceutical active ingredient (API) development.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring phenacyl-based structures.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Polymer and Material Science: Employed in the creation of monomers and functional additives for high-performance polymers and advanced materials.
• Dye and Pigment Manufacturing: Utilized as an intermediate in the production of specialized dyes and organic pigments.
• Chemical Research & Development: A fundamental reagent for academic and industrial R&D exploring new organic reactions and molecular architectures.

Basic Information

Product Name	4-tert-Butylphenacyl Chloride
CAS No.	21886-62-4
Molecular Formula	C12H15ClO
Molecular Weight	210.70 g/mol
Synonyms	1-(4-tert-Butylphenyl)-2-chloroethanone; 2-Chloro-1-[4-(1,1-dimethylethyl)phenyl]ethanone; 4-tert-Butyl-ω-chloroacetophenone; p-tert-Butylphenacyl Chloride; 4-(tert-Butyl)phenacyl Chloride; 2-Chloro-1-(4-tert-butylphenyl)ethanone; α-Chloro-4-tert-butylacetophenone
EINECS	Contact for details

Quality Control

Our 4-tert-Butylphenacyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all test results are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.