Description

Phenylbis[4-(trifluoromethyl)phenyl]methanol is a specialized fluorinated organic compound characterized by a central tertiary alcohol flanked by aromatic rings bearing trifluoromethyl groups. This structure is highly valued for its role as a key synthetic intermediate in the development of advanced materials and pharmaceuticals, where its unique electronic and steric properties are leveraged. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl groups contribute to improved lipophilicity and biological activity.
• Ligand Precursor: Serves as a starting material for the preparation of sophisticated ligands used in catalysis, such as for cross-coupling reactions or asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for developing novel polymers and liquid crystals with specific optical or electronic properties.
• Organic Electronic Materials: Explored in the development of charge-transport materials or emitters for OLEDs (Organic Light-Emitting Diodes) due to its fluorinated aromatic structure.
• Chemical Research & Development: Employed in academic and industrial R&D settings for method development and exploring new reaction pathways involving fluorinated compounds.

Basic Information

Product Name	Phenylbis[4-(trifluoromethyl)phenyl]methanol
CAS No.	21856-97-3
Molecular Formula	C21H13F9O
Molecular Weight	452.32 g/mol
Synonyms	Phenylbis[4-(trifluoromethyl)phenyl]methanol; [Phenylbis(4-trifluoromethylphenyl)]methanol; α,α-Bis[4-(trifluoromethyl)phenyl]benzenemethanol; Tris(4-trifluoromethylphenyl)methanol (common name); Benzhydrol, α,α-bis[4-(trifluoromethyl)phenyl]-; 1,1',1''-Methanetriyltris[4-(trifluoromethyl)benzene] (alternative); α-(4-Trifluoromethylphenyl)-α-phenyl-4-(trifluoromethyl)benzenemethanol
EINECS	Contact for details

Quality Control

Our Phenylbis[4-(trifluoromethyl)phenyl]methanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), identity confirmation (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable material for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation to maintain optimal purity and stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.