Description

3H-3-Benzazepine-3-Carbonyl Chloride, 1,2,4,5-Tetrahydro- (8Ci,9Ci) is a specialized organic intermediate featuring a reactive carbonyl chloride group on a benzazepine scaffold. This compound is a critical building block in advanced organic synthesis, enabling the efficient introduction of the benzazepine moiety into target molecules. It is primarily sought after by pharmaceutical research and fine chemical synthesis laboratories for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of central nervous system (CNS) active agents and other therapeutic candidates.
• Peptidomimetic Research: Used to incorporate constrained, bicyclic amino acid analogs into peptide chains to study structure-activity relationships.
• Ligand Synthesis for Receptor Studies: Serves as a building block for creating high-affinity ligands for neurological and GPCR targets.
• Chemical Biology Probes: Employed in the development of activity-based probes and molecular tools for studying enzyme function.
• Fine Chemical Synthesis: A versatile reagent for constructing complex heterocyclic frameworks in multi-step synthetic routes.
• Agrochemical Research: Potential intermediate in the discovery of new crop protection agents with novel modes of action.

Basic Information

Product Name	3H-3-Benzazepine-3-Carbonyl Chloride, 1,2,4,5-Tetrahydro- (8Ci,9Ci)
CAS No.	21856-18-8
Molecular Formula	C11H10ClNO
Molecular Weight	207.66 g/mol
Synonyms	1,2,4,5-Tetrahydro-3H-3-benzazepine-3-carbonyl chloride; 3-Benzazepine-3-carbonyl chloride, 1,2,4,5-tetrahydro-; 1,2,4,5-Tetrahydro-3H-3-benzazepine-3-carbonyl chloride; 3-(Chlorocarbonyl)-1,2,4,5-tetrahydro-3H-3-benzazepine; 3-Carbamoylchloride-1,2,4,5-tetrahydro-3H-3-benzazepine; Tetrahydrobenzazepine-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our high-purity 3H-3-Benzazepine-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.