Description

2-Chloro-4-isothiocyanatobenzonitrile is a versatile and reactive organic intermediate featuring both an isothiocyanate and a nitrile functional group on a chlorinated aromatic ring. This unique structure makes it a valuable building block for synthesizing more complex molecules, particularly in the development of agrochemicals and pharmaceuticals. It is primarily sought after by research chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the reactivity of the isothiocyanate group.
• Pharmaceutical Building Block: Used in medicinal chemistry for the construction of heterocyclic compounds and potential drug candidates, especially those targeting specific enzymes or receptors.
• Chemical Research & Development: Serves as a versatile synthon in organic synthesis for creating libraries of compounds in discovery programs.
• Dye and Pigment Synthesis: Can be utilized in the production of specialized dyes and pigments due to its aromatic core and functional groups.
• Ligand and Chelator Preparation: The nitrile and isothiocyanate groups can be further modified to create complexing agents for metals.

Basic Information

Product Name	2-Chloro-4-isothiocyanatobenzonitrile
CAS No.	21724-83-4
Molecular Formula	C8H3ClN2S
Molecular Weight	194.64 g/mol
Synonyms	2-Chloro-4-isothiocyanatobenzonitrile; 4-Isothiocyanato-2-chlorobenzonitrile; 2-Chloro-4-isothiocyanato-benzonitrile; Benzonitrile, 2-chloro-4-isothiocyanato-; 2-Chloro-4-isothiocyanato benzonitrile; 2-Chloro-4-thiocyanatobenzonitrile (common misnomer); 2-Chloro-4-isothiocyanato-benzene carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-isothiocyanatobenzonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.