Description

3β-[(6-Deoxy-2-O,3-o-Isopropylidene-α-L-Mannopyranosyl)Oxy]-14-Hydroxybufa-4,20,22-Trienolide is a high-purity, specialized cardiac glycoside derivative with a complex steroidal structure. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential biological activity. It serves as a critical intermediate or reference standard for scientists in medicinal chemistry and pharmacology. Target users include R&D laboratories, academic institutions, and fine chemical manufacturers focused on cardiovascular drug discovery and biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel cardiac glycoside-based therapeutics.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and compound identification.
• Medicinal Chemistry Research: A valuable tool for structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Biochemical Studies: Employed in in-vitro assays to investigate interactions with biological targets such as the Na+/K+-ATPase enzyme.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and natural product chemistry.

Basic Information

Product Name	3β-[(6-Deoxy-2-O,3-o-Isopropylidene-α-L-Mannopyranosyl)Oxy]-14-Hydroxybufa-4,20,22-Trienolide
CAS No.	21590-25-0
Molecular Formula	C36H52O9
Molecular Weight	628.80 g/mol
Synonyms	14-Hydroxy-3β-[(6-deoxy-2,3-O-isopropylidene-α-L-mannopyranosyl)oxy]bufa-4,20,22-trienolide; 3β-[(6-Deoxy-2,3-O-isopropylidene-α-L-mannopyranosyl)oxy]-14-hydroxybufa-4,20,22-trienolide; Bufalin 3-(6-deoxy-2,3-O-isopropylidene-α-L-mannopyranoside); 14-Hydroxybufalin 3-(6-deoxy-2,3-O-isopropylidene-α-L-mannopyranoside); Aconitine-related compound T3; Cardiac glycoside derivative 21590-25-0.
EINECS	Contact for details

Quality Control

Our 3β-[(6-Deoxy-2-O,3-o-Isopropylidene-α-L-Mannopyranosyl)Oxy]-14-Hydroxybufa-4,20,22-Trienolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR/MS for structural confirmation, to ensure it meets exacting research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (typically 15-25°C) in a dry environment. For long-term storage, consider storing desiccated at -20°C. Handle and store in accordance with good laboratory practices for potent bioactive compounds.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.