Description

Icrf-175 is a potent and specific chelating agent, known chemically as (+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane. This compound is of significant interest in biochemical and pharmaceutical research due to its ability to selectively bind metal ions, influencing critical biological pathways. It is primarily utilized by research institutions and pharmaceutical developers investigating metalloenzyme function, chelation therapy, and novel therapeutic mechanisms.

Application

• Biochemical Research: Used as a specific chelator in enzymatic studies to investigate the role of divalent metal ions in protein function and stability.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the research and development of novel chelation-based therapeutics.
• Metalloenzyme Inhibition: Applied in vitro to inhibit metal-dependent enzymes, aiding in the study of metabolic pathways and disease mechanisms.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in bioinorganic chemistry and medicinal chemistry.

Basic Information

Product Name	Icrf-175
CAS No.	21454-02-4
Molecular Formula	C11H16N4O4
Molecular Weight	268.27 g/mol
Synonyms	(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; ICRF-175; NSC-169780; ICRF 175; Razoxane Impurity; Dexrazoxane Impurity; (+)-ICRF-175; 1,2-Bis(3,5-dioxopiperazinyl)propane
EINECS	Contact for details

Quality Control

Our Icrf-175 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.