Description

3β-[(4-o-β-D-Glucopyranosyl-6-Deoxy-α-L-Mannopyranosyl)Oxy]-12β,14-Dihydroxybufa-4,20,22-Trienolide is a high-purity, structurally complex bufadienolide glycoside, a class of compounds known for their potent biological activity. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of cardiac glycosides and their derivatives. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers requiring a reliable supply of specialized reference standards and active pharmaceutical ingredient (API) intermediates.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in drug development.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the research and synthesis of novel therapeutic agents, particularly those targeting cardiovascular functions.
• Biochemical Research: Employed in pharmacological and toxicological studies to investigate the structure-activity relationships (SAR) of bufadienolides.
• Analytical Chemistry: Acts as a high-purity standard for HPLC, LC-MS, and other chromatographic analyses in academic and industrial laboratories.
• Preclinical Development: Utilized in the early-stage development of potential drug candidates derived from natural product scaffolds.

Basic Information

Product Name	3β-[(4-o-β-D-Glucopyranosyl-6-Deoxy-α-L-Mannopyranosyl)Oxy]-12β,14-Dihydroxybufa-4,20,22-Trienolide
CAS No.	21305-13-5
Molecular Formula	C36H52O14
Molecular Weight	708.79 g/mol
Synonyms	Telocinobufagin 3-O-[β-D-glucopyranosyl-(1→4)-6-deoxy-α-L-mannopyranoside]; Desacetylcinobufagin 3-O-[β-D-glucopyranosyl-(1→4)-6-deoxy-α-L-mannopyranoside]; Bufadienolide glycoside; 12β,14-Dihydroxy-3β-[(4-O-β-D-glucopyranosyl-6-deoxy-α-L-mannopyranosyl)oxy]bufa-4,20,22-trienolide; Cinobufagin derivative; 21305-13-5; Telocinobufagin glucoside
EINECS	Contact for details

Quality Control

Our 3β-[(4-o-β-D-Glucopyranosyl-6-Deoxy-α-L-Mannopyranosyl)Oxy]-12β,14-Dihydroxybufa-4,20,22-Trienolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.