Description

3'-(Acetylamino)-3'-Deoxyadenosine is a chemically modified nucleoside analog of adenosine, where the 3'-hydroxyl group is replaced by an acetylamino moiety. This structural modification makes it a valuable intermediate and research tool in the development of novel antiviral and anticancer agents, particularly in the study of nucleotide metabolism and nucleic acid synthesis. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on nucleoside chemistry and medicinal chemistry.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate in the design and synthesis of novel nucleoside-based therapeutics.
• Antiviral Agent Studies: Used in biochemical research to investigate mechanisms of action and develop potential inhibitors of viral polymerases.
• Oncology Research: Explored as a precursor or analog in the development of chemotherapeutic agents targeting DNA replication.
• Biochemical Tool: Employed in enzymatic studies to probe the activity and specificity of nucleoside kinases and other metabolic enzymes.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Academic Research: Used in university laboratories for teaching and advanced research in bioorganic and medicinal chemistry.

Basic Information

Product Name	3'-(Acetylamino)-3'-Deoxyadenosine
CAS No.	21299-78-5
Molecular Formula	C₁₂H₁₆N₆O₄
Molecular Weight	308.29 g/mol
Synonyms	3'-Acetamido-3'-deoxyadenosine; 3'-N-Acetyl-3'-deoxyadenosine; 3'-Deoxy-3'-(acetylamino)adenosine; 3'-Amino-3'-deoxy-N-acetyladenosine; N-[3-Deoxy-β-D-ribofuranosyl)adenin-3-yl]acetamide; 3'-Acetylamino-3'-deoxyadenosine; Adenosine, 3'-(acetylamino)-3'-deoxy-
EINECS	Contact for details

Quality Control

Our 3'-(Acetylamino)-3'-Deoxyadenosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.