Description

(-)-Indolmycin CAS NO 21200-24-8 is a naturally occurring antibiotic compound belonging to the indole alkaloid class. It is a potent and specific inhibitor of bacterial tryptophanyl-tRNA synthetase, making it a valuable tool for biochemical research and a lead compound for novel antibacterial development. This high-purity material is essential for pharmaceutical R&D, microbiology studies, and the investigation of novel antimicrobial mechanisms.

Application

• Biochemical Research: Used as a specific probe to study bacterial protein synthesis, particularly the function of tryptophanyl-tRNA synthetase.
• Antimicrobial Mechanism Studies: Serves as a reference standard in research exploring new pathways for antibiotic development and resistance mechanisms.
• Pharmaceutical R&D: Acts as a lead compound or intermediate in the discovery and synthesis of new antibacterial agents.
• Microbiology: Employed in selective media or as a tool to study bacterial growth inhibition under controlled conditions.
• Enzyme Inhibition Assays: Utilized in high-throughput screening and in vitro assays to identify and characterize new enzyme inhibitors.

Basic Information

Product Name	(-)-Indolmycin
CAS No.	21200-24-8
Molecular Formula	C16H19N3O3
Molecular Weight	301.34 g/mol
Synonyms	(-)-Indolmycin; L-Indolmycin; NSC 163501; Antibiotic 13880A; Indolmycin; (2S)-2-Amino-3-[1-(3-hydroxy-2-methyl-1-oxo-4-indolyl)ethyl]butanoic acid; Tryptophanyl-tRNA synthetase inhibitor
EINECS	Contact for details

Quality Control

Our (-)-Indolmycin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.