Description

Indolmycin is a potent, naturally occurring antibiotic compound belonging to the tryptophan-derived class of microbial metabolites. Its primary value lies in its specific and potent inhibitory activity against bacterial tryptophanyl-tRNA synthetase, making it a critical tool for biochemical research and a promising scaffold for novel antimicrobial development. This product is essential for pharmaceutical R&D laboratories, academic institutions, and biotechnology companies focused on antibiotic discovery, bacterial protein synthesis studies, and mechanism-of-action research. Indolmycin CAS NO 21193-77-1 is supplied as a high-purity reference standard to support these advanced scientific endeavors.

Application

• Biochemical Research: Used as a specific inhibitor to study bacterial protein synthesis, particularly the function of tryptophanyl-tRNA synthetase.
• Antibiotic Discovery & Development: Serves as a lead compound and reference standard in the search for new classes of antimicrobial agents targeting aminoacyl-tRNA synthetases.
• Microbiology Studies: Employed in research to understand bacterial resistance mechanisms and to characterize the spectrum of activity against various bacterial strains.
• Pharmaceutical Reference Standard: Utilized as a certified reference material (CRM) for quality control, method development, and validation in analytical laboratories.
• Enzyme Inhibition Assays: Acts as a potent and selective inhibitor in high-throughput screening (HTS) assays and enzymatic studies.

Basic Information

Product Name	Indolmycin
CAS No.	21193-77-1
Molecular Formula	C14H17N3O3
Molecular Weight	275.31 g/mol
Synonyms	Indolmycin; Antibiotic 21,723; NSC 172051; (S)-2-Amino-3-(1H-indol-3-yl)-N-[(2S,3S)-3-hydroxy-1-oxo-1-(phenylmethoxy)butan-2-yl]propanamide; L-Tryptophan, N-[(2S,3S)-3-hydroxy-1-oxo-1-(phenylmethoxy)butyl]-; Tryptophanyl-tRNA synthetase inhibitor
EINECS	Contact for details

Quality Control

Our Indolmycin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all test results against our stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.