Description

(25S)-5β-Spirostane-2β,3α,27-Triol CAS NO 21152-89-6 is a high-purity, steroidal sapogenin derivative characterized by its specific hydroxylation pattern at the 2β, 3α, and 27 positions. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard for analytical and research purposes. It is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for the development of novel steroid-based therapeutics and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex steroid drugs and hormone analogs.
• Reference Standard: Used for method development, validation, and quality control in analytical laboratories (HPLC, GC, LC-MS).
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor binding assays.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of specialized steroidal compounds with potential biological activity.
• Academic Research: Utilized in universities and research institutes for chemical and pharmacological studies related to spirostane derivatives.

Basic Information

Product Name	(25S)-5β-Spirostane-2β,3α,27-Triol
CAS No.	21152-89-6
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	(25S)-Spirostane-2β,3α,27-triol; 2β,3α,27-Trihydroxy-5β-spirostan; (25S)-2β,3α,27-Trihydroxyspirostan-5β-ol; Tigogenin triol derivative; 5β-Spirostane-2β,3α,27-triol, (25S)-; 21152-89-6; Steroidal sapogenin triol
EINECS	Contact for details

Quality Control

Our (25S)-5β-Spirostane-2β,3α,27-Triol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.