Description

8-Hydroxyadenine is a purine derivative and a key nucleobase analog with significant biochemical relevance. This compound is valued for its role as a research chemical in studying nucleic acid structure, modification, and repair mechanisms. It is primarily utilized by research institutions and pharmaceutical companies engaged in biochemical research, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a standard or reagent in studies of DNA/RNA damage, repair pathways, and mutagenesis.
• Medicinal Chemistry: Serves as a building block or intermediate in the synthesis of nucleoside analogs for potential pharmaceutical applications.
• Enzymology Studies: Employed as a substrate or inhibitor to investigate the activity of enzymes like oxidases, deaminases, and methyltransferases.
• Diagnostic Development: Potential use in developing assays and probes for detecting specific enzymatic activities or nucleic acid modifications.
• Academic Research: Fundamental tool in university laboratories for teaching and advanced research in bioorganic chemistry and molecular biology.

Basic Information

Product Name	8-Hydroxyadenine
CAS No.	21149-26-8
Molecular Formula	C5H5N5O
Molecular Weight	151.13 g/mol
Synonyms	8-Oxoadenine; 8-Oxo-adenine; Hypoxanthine, 2-amino-; 2-Amino-6,8-dihydroxypurine; 8-Hydroxy-adenine; Adenine, 8-hydroxy-; 1H-Purin-6-amine, 7,8-dihydro-8-oxo-; 8-Oxo-7,8-dihydroadenine
EINECS	Contact for details

Quality Control

Our 8-Hydroxyadenine is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure high purity and consistency, with specifications tailored to research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and meet the exacting requirements of scientific research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.