Description

(-)-Virginiamycin M2 CAS NO 21102-49-8 is a specific stereoisomer of the Virginiamycin M2 component, a key member of the streptogramin family of antibiotics. This high-purity compound is critical for research and development in antimicrobial studies and serves as a primary reference standard. It is essential for pharmaceutical manufacturers, analytical laboratories, and academic institutions focused on developing novel antibacterial agents, studying resistance mechanisms, and ensuring quality control of related antibiotic formulations.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of Virginiamycin-based drug substances and products.
• Antimicrobial Research: Serves as a critical tool in microbiological research for studying the efficacy, mode of action, and resistance patterns of streptogramin antibiotics.
• Veterinary Medicine Development: Employed in R&D for animal health products, particularly growth promoters and treatments for Gram-positive bacterial infections.
• Analytical Method Development: Essential for developing and validating high-performance liquid chromatography (HPLC) and other analytical methods in quality control laboratories.
• Biochemical Studies: Used to investigate protein synthesis inhibition at the ribosomal level and structure-activity relationships (SAR) within the streptogramin class.

Basic Information

Product Name	(-)-Virginiamycin M2
CAS No.	21102-49-8
Molecular Formula	C28H35N3O7S
Molecular Weight	557.66 g/mol
Synonyms	Virginiamycin M2; Virginiamycin M2; Antibiotic M 2; Mikamycin M2; Pristinamycin IIA; Streptogramin M2; Antibiotic 899; Vernamycin B; E 129; (-)-Pristinamycin IIA; (3R,4S,5E,10E,12E,14S)-14-[[(2R,3R,4R,5S,6R)-5-(Dimethylamino)-4-hydroxy-6-methyloxan-2-yl]oxy]-4-hydroxy-3,7,15-trimethyl-16-oxa-8,11-diazabicyclo[12.3.1]octadeca-1(17),5,10,12,15-pentaene-2,9,18-trione
EINECS	244-197-8

Quality Control

Our (-)-Virginiamycin M2 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets the stringent requirements for use as a reference standard. Certificates of Analysis (COA) with detailed chromatograms and test results are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Optical Rotation	-90° to -110° (c=1 in methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.