Description

(3A,5B,6A,12A)-3,6,12-Trihydroxy-Cholan-24-Oic Acid is a hydroxylated bile acid derivative, a key intermediate in the synthesis of more complex steroid compounds. This high-purity intermediate is critical for ensuring the quality and consistency of downstream pharmaceutical and research products. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for the development of therapeutic agents and biochemical research.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of ursodeoxycholic acid (UDCA) analogs and other therapeutic bile acids.
• Biochemical Research: Used as a reference standard and a precursor in studies of bile acid metabolism, liver function, and cholesterol homeostasis.
• Fine Chemical Synthesis: Serves as a chiral starting material for the production of complex steroid-based molecules in advanced organic synthesis.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and development of novel hepatoprotective and choleretic agents.
• Diagnostic Reagents: Can be utilized in the formulation of calibration standards and reagents for clinical diagnostic assays.

Basic Information

Product Name	(3A,5B,6A,12A)-3,6,12-Trihydroxy-Cholan-24-Oic Acid
CAS No.	21066-18-2
Molecular Formula	C24H40O6
Molecular Weight	424.57 g/mol
Synonyms	3α,6α,12α-Trihydroxy-5β-cholan-24-oic Acid; 3,6,12-Trihydroxycholanic Acid; Hyocholic Acid; 3α,6α,12α-Trihydroxy-5β-cholanoic Acid; 5β-Cholan-24-oic acid, 3α,6α,12α-trihydroxy-; (3α,5β,6α,12α)-3,6,12-Trihydroxycholan-24-oic Acid
EINECS	244-189-5

Quality Control

Our (3A,5B,6A,12A)-3,6,12-Trihydroxy-Cholan-24-Oic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.