Description

2-Isothiocyanato-Pentanedioic Acid Dimethyl Ester is a versatile bifunctional organic building block containing both an isothiocyanate and diester functional groups. This compound is valued for its role as a key intermediate in the synthesis of complex heterocyclic compounds and functionalized amino acid derivatives. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor for the synthesis of heterocyclic compounds with potential biological activity, including thiazolidinones and related fused ring systems.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive isothiocyanate group.
• Peptidomimetics & Bioconjugation: Serves as a building block for creating modified peptides and for bioconjugation applications due to its ability to react with amines.
• Material Science Research: Employed in the development of specialty polymers and functional materials that require specific chemical linkages.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and protein labeling.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and for exploring new reaction pathways.

Basic Information

Product Name	2-Isothiocyanato-Pentanedioic Acid Dimethyl Ester
CAS No.	21055-50-5
Molecular Formula	C9H13NO4S
Molecular Weight	231.27 g/mol
Synonyms	Dimethyl 2-Isothiocyanatoglutarate; Dimethyl 2-Isothiocyanatopentanedioate; 2-Isothiocyanatoglutaric Acid Dimethyl Ester; Glutaric Acid, 2-Isothiocyanato-, Dimethyl Ester; NSC 163063
EINECS	Contact for details

Quality Control

Our 2-Isothiocyanato-Pentanedioic Acid Dimethyl Ester is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.